Key Differences Between Similac Total Comfort vs Pro-Total Comfort
| Criteria | Similac Total Comfort | Similac Pro-Total Comfort |
|---|---|---|
| Designed for | Delicate tummies | Delicate tummies and immunity support |
| Protein | Partially Hydrolyzed Whey Protein | Partially Hydrolyzed Whey Protein |
| Prebiotics | Yes (Fructooligosaccharides) | Yes (Fructooligosaccharides and 2′-FL HMO) |
| Probiotics | No â | No â |
| Carbohydrate Content | 10.7g (from Corn Maltodextrin) | 10.7g (from Corn Maltodextrin) |
| Fat Content | 5.4g (High Oleic Safflower Oil, Soy Oil, Coconut Oil) | 5.4g (High Oleic Safflower Oil, Soy Oil, Coconut Oil) |
| Palm Olein Oil | No â | No â |
| Special Addition | OptiGRO (DHA, Lutein, Vitamin E) | 2′-FL HMO |
| Price | $$ | $$$ |
Choosing the right baby formula can significantly impact your little oneâs growth and development.
This post will analyze the ingredients and nutritional composition of two similar formulas, Similac Total Comfort and Similac Pro-Total Comfort, to give you the information you need to decide.
Let’s get after it!
*Related read: Similac Sensitive vs Total Comfort
Our Short Answer
After analyzing both formulas, it is clear that they are family.
Both have the same nutritional profile, and this is the only important difference:
– Similac Pro-Total Comfort adds 2′-FL HMO, a prebiotic found in breast milk, which is very beneficial for a baby’s microbiota.
That is why it comes out on top in this comparison. That is, if the price difference doesn’t put you off.
We encourage you to look at our recommended alternatives below.
With over 100,000 orders delivered globally since 2019, Organic's Best offers clean, safe, and nutritionally rich formulas and snacks.
Free shipping over $100, commitment to freshness and authenticity.
- Express delivery in 2 to 5 business days
- Sourcing from European manufacturers
- Minimum shelf life of 6 months
- Climate-Controlled Warehouse
Give your little one the best start.
CODE 'BLW' for a 5% discount in all orders
Overview of the Two Formulas
Similac Total Comfort is gentle, designed for delicate tummies, with partially hydrolyzed protein, prebiotics, and OptiGRO for overall development.
Similac Pro-Total Comfort has 2′-FL HMO, and supports the immune system, brain, and eye development with DHA as well.
Similac Total Comfort
Similac Total Comfort is a specially designed infant formula that provides complete nutrition for delicate tummies.
It is formulated to be gentle, with partially hydrolyzed protein for easier digestion – a significant relief for babies who cannot tolerate other milk-based formulas.
Besides, it contains prebiotics for softer stools and is friendly for infants with lactose sensitivity.
Moreover, it boasts OptiGRO, an exclusive blend of DHA, Lutein, and Vitamin E that supports your baby’s overall growth, brain, eye, and immune system development.
It is gluten-free, accepted in-store with HSA/FSA cards, and SNAP eligible.
Similac Pro-Total Comfort
Similac Pro-Total Comfort, on the other hand, is an easy-to-digest formula with 2′-FL human milk oligosaccharide (2′-FL HMO), an immune-nourishing prebiotic reminiscent of that found in breast milk. This helps support the baby’s developing immune system.
It is a gentle formula ideal for babies with difficulty tolerating other milk-based formulas, with issues such as fussiness, gas, and crying.
It contains no palm olein oil, supporting excellent calcium absorption, and is designed to support the baby’s brain and eyes, with the addition of DHA and Lutein, essential ingredients found in breast milk.
It can be purchased using an in-store HSA/FSA card like its counterpart.
Nutritional Composition
Similac Total Comfort and Similac Pro-Total Comfort have the same protein content (partially hydrolyzed whey protein), carbohydrate content (10.7g from corn maltodextrin), and fat content (5.4g with beneficial oils).
They do not contain lactose and have no added palm oil.
Protein Content
Both Similac Total Comfort and Similac Pro-Total Comfort contain 2.32 grams of protein in every 5 fluid ounces serving, which meets infants’ growing demands.
The proteins in these formulations are based on whey protein hydrolysate, which is partially broken down to facilitate easy digestion.
Both formulas have the same protein source: partially hydrolyzed whey protein in the same quantities.
This means both are great for those babies with problems digesting cow’s milk protein, but not for those with diagnosed CMPA. In that case, your baby would need an extensively hydrolyzed formula.
*Read: Partially vs extensively hydrolyzed formulas
Carbohydrate Content
Each serving of both formulas supplies 10.7 grams of carbohydrates.
The primary carbohydrate source in these products is Corn Maltodextrin, a highly digestible carbohydrate derived from corn that provides infants with the energy they need.
Both formulas are designed for babies with digestive issues, including lactose sensitivity.
That is why neither of these two formulas have lactose and use a substitute like corn maltodextrin, so babies with problems digesting lactose can digest these formulas without problems.
It’s important to mention that corn maltodextrin is a better alternative to corn syrup solids, like many other formulas manufactured in the US. This is because it has less sugar content and has a more neutral flavor.
Fats and Oils
The fat content is crucial for infant growth, brain development, and energy.
Both formulas provide 5.4 grams of fat in every 5 fluid ounces serving.
The fat sources in these formulas blend High Oleic Safflower Oil, Soy Oil, and Coconut Oil.
Both formulas contain Schizochytrium sp. oil and M. Alpina Oil, rich sources of beneficial fatty acids such as DHA and ARA, crucial for brain and eye development.
No difference in fat content either.
No addition of non-organic palm oil or palm olein, which is what we want to see.
Probiotics and Prebiotics
Similac Total Comfort and Similac Pro-Total Comfort include short-chain fructooligosaccharides to support a healthy gut, but the Pro version includes 2′-FL HMOs.
Neither formula explicitly contains probiotics.
Both Similac Total Comfort and Similac Pro-Total Comfort are packed with prebiotics.
Prebiotics are fiber compounds that pass undigested through the upper part of the gastrointestinal tract and stimulate the growth or activity of beneficial bacteria that colonize the baby’s gut, thus improving health.
The Pro-Total Comfort contains 2′-FL HMO, a prebiotic found in breast milk, while both formulas have Short-Chain Fructooligosaccharides (prebiotic).
Neither formula explicitly contains probiotics, beneficial bacteria that aid digestion and support a healthy gut environment.
*Read: Prebiotics and probiotics in baby formula
Best Places to Buy Simiilac Total Comfort vs Pro-Total Comfort
Similac Total Comfort
Buy Similac Total Comfort at Target
Buy Similac Total Comfort at Walmart
Similac Pro-Total Comfort
Buy Similac Pro-Total Comfort at Target
Buy Similac Pro-Total Comfort at Walmart
What are the best alternatives to Similac Total Comfort and Pro-Total Comfort?
Hipp HA is our top pick for a hypoallergenic formula. It is organic and specially designed for infants at risk of allergies. It ensures that large protein molecules, which could cause allergic reactions, are split into smaller sizes for easier digestion. *Read: Hipp HA vs Similac Alimentum
Hipp Comfort and Hipp Anti-Reflux are excellent alternatives for babies experiencing digestive issues. Hipp Comfort is particularly designed to tackle constipation and colic symptoms, while Hipp Anti-Reflux is formulated to reduce spit-up and reflux symptoms in babies. *Read: Hipp Comfort vs Hipp Anti-Reflux
High-quality goat milk formulas can be easier to digest alternatives for babies without Cow’s Milk Protein Allergy (CMPA). Kendamil Goat and Nannycare offer such options. Both are known for being gentle on the stomach and provide beneficial nutrients. *Read: Nannycare vs Kendamil
Last Words
We hope this comparison between Similac Total Comfort and Pro-Comfort has helped you make an informed decision.
Remember that there are other suitable and organic alternatives that we recommend checking out.
See you around!
We’re Maria and Alberto, a married couple and educators who are nutrition enthusiasts. Even before we had kids, we were already crazy about nutrition.
We’d read scientific articles, watch videos from nutritionists, and spend hours listening to nutrition podcasts.
Today, we continue doing this, but in a different way, as we’ve learned to sift through the noise and trends. Nutrition, like any other field of knowledge, the more you read and learn, the more you develop a comprehensive understanding of reality, and that’s what has happened to us.
Before having our first child, we focused on learning everything we could about child nutrition, using the same techniques we had already employed, backed by our extensive knowledge in nutrition.
Our mission is to help other parents with their children’s nutrition, to help them become the best versions of themselves.
If we are what we eat and drink, which is absolutely true, let’s do it right!
