Similac-Pure-Bliss-vs-Enfamil-Enspire

Key Differences Between Similac Pure Bliss and Enfamil Enspire

CriteriaSimilac Pure BlissEnfamil Enspire
Milk SourceMilk from free-range, grass-fed cows primarily from Irish family-owned farmsStandard source
Added IngredientsNoneMFGM (Milk Fat Globule Membrane) and Lactoferrin
Palm OleinNoYes
Whey-to-Casein Ratio48:5265:35
Protein (per 5.3 fl oz)2.07g (from nonfat milk and whey concentrate)2.1g (from nonfat milk, whey concentrate, and whey protein-lipid concentrate)
Carbs (per 5.3 fl oz)10.7g (mainly lactose)11.2g (mainly lactose)
Fats (per 5.3 fl oz)5.6g (from sunflower, soy, coconut oil)5.3g (from palm olein, coconut, soy, sunflower oils)
Probiotics and PrebioticsIncludes galactooligosaccharides (prebiotic)Contains galactooligosaccharides, polydextrose (prebiotics), and probiotics
Unique FeaturesNatural breast milk resemblance, no artificial hormones, and palm olein oil. Non-GMOMimics colostrum and breast milk with lactoferrin for immunity and MFGM for mental development. Non-GMO

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This article aims to compare two popular formulas in the US: Similac Pure Bliss vs Enfamil Enspire.

We will analyze their ingredients and nutritional compositions to help you make an informed decision.

Let’s get after it!

Related read: Similac Pure Bliss vs Pro-Advance

Our Short Answer

Both Similac Pure Bliss and Enfamil Enspire are designed for infants without gastrointestinal problems and are both ordinary formulas.

In our opinion, Pure Bliss wins this comparison for the following reasons:

  • It uses better quality milk, expressed from free-range cows.
  • It does not add palm olein to its formula

Enfamil Enspire may win in other people’s eyes because:

  • It adds MFGM (Milk Fat Globule Membrane) and lactoferrin to its formula, two ingredients associated with fewer digestive problems and found in breast milk.
  • It has a better whey-to-casein ratio.

That said, our recommendation as mentioned above is Pure Bliss, as we consider the origin of the ingredients to be the most important factor when choosing any type of nutrition for our baby.

Before you decide, we recommend you to read about the alternatives mentioned below, since there are better options in the market.

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Overview of the Two Formulas

Similac Pure Bliss offers natural breast milk resemblance, excluding artificial hormones and palm olein oil, sourced from grass-fed cows.

Enfamil Enspire mimics colostrum and breast milk, with lactoferrin for immunity and MFGM for mental development.

Both cater to dietary needs and are non-GMO.

Similac Pure Bliss

Similac Pure Bliss is an infant formula designed to be close to natural breast milk. The creators took special care to provide nutrition that is digestive-friendly and gentle on little tummies. They made sure to exclude any artificial growth hormones and has no added antibiotics or palm olein oil, thus ensuring a non-GMO status.

The formula’s design is quite impressive. It starts with fresh milk from grass-fed cows, primarily sourced from family-owned Irish farms where these cows freely graze outdoors. This sounds nice, doesn’t it? Well, its benefits appeal too; by providing DHA and ARA, the formula supports brain and eye development.

Its dietary needs cover a broad range, catering for Kosher, Certified Gluten Free, and Halal. Talk about inclusion!

Enfamil Enspire

Enfamil Enspire is another baby formula milk powder that takes a page from nature’s book. With components found in colostrum and breast milk, it aims to support your little one’s growth in the most natural way.

One of its unique features is the presence of lactoferrin, a component also found in breast milk that strengthens the immune system, along with MFGM, which helps support your baby’s mental development. It also contains DHA, just like mother’s milk.

Enfamil Enspire is the first and only formula with the inclusion of Lactoferrin, and it’s a non-GMO baby formula. This brand is recommended by pediatricians and is created to provide complete nutrition for your baby up to their first 12 months. It covers dietary needs with its natural flavor and non-GMO Project Verified status, making it a strong contender in the baby formula scene.

Nutritional Composition

Similac Pure Bliss: Protein from nonfat milk and whey concentrate, 2.07g protein in 5.3 fl oz, 48:52 whey-to-casein ratio. Carbs mainly lactose, 10.7g. Fats: 5.6g from sunflower, soy, coconut oil.

Enfamil Enspire: 2.1g protein in 5 fl oz, with whey protein-lipid concentrate, 65:35 whey-to-casein ratio. Carbs mainly lactose, 11.2g. Fats: 5.3g from palm olein, coconut, soy, sunflower oils.


Protein Content

In every 5.3 fl oz serving, Similac Pure Bliss has 2.07g of protein. The protein in this formula is derived from nonfat milk and whey protein concentrate. These protein sources are easily digestible and have a similar composition to the proteins found in breast milk.

On the other hand, Enfamil Enspire has a slightly higher protein content of 2.1g in every 5 fl oz serving. The protein in Enfamil Enspire comes from nonfat milk and whey protein concentrate, like in Similac Pure Bliss, but it also contains whey protein-lipid concentrate. Including whey protein-lipid concentrate is believed to boost the formula’s overall protein content.

Apart from the fact that Pure Bliss uses a better milk source, the only difference in protein is the whey-to-casein ratio of both formulas.

Pure Bliss has a 48:52 and Enspire a 65:35. This gives Enspire the upper hand since a whey-to-casein ratio closer to that of mature breast milk (60:40) is considered more easily digestible.

Carbohydrate Content

In terms of carbohydrate content, Similac Pure Bliss contains 10.7g per 5.3 fl oz serving, primarily sourced from lactose. Enfamil Enspire has a relatively higher carbohydrate content of 11.2g per 5 fl oz serving. Enfamil also obtains its carbohydrates mainly from lactose.

Lactose is a naturally occurring sugar found in cow’s milk and human milk, and it is the primary carbohydrate source in many baby formulas. It is excellent for gut health and aids in the absorption of calcium and magnesium, essential for your baby’s growth.

No differences here whatsoever, except for the fact that Pure Bliss uses milk from grass-fed cows.

Fats and Oils

The fat content in a 5.3 fl oz serving of Similac Pure Bliss is 5.6g. The fat in Similac Pure Bliss comes from high oleic sunflower, soy, and coconut oil. On the other side, Enfamil Enspire has slightly less fat, with 5.3g per 5 fl oz serving. The fats in Enfamil Enspire are provided by palm olein, coconut, soy, and high oleic sunflower oils.

Fats and oils in baby formulas play a crucial role in your baby’s development. They provide energy, aid in the absorption of vitamins, and are essential for brain development.

Pure Bliss easily wins the fat content battle for avoiding palm olein. This ingredient, which Enspire uses, is a controversial one, since studies have linked it with poor calcium absorption when consumed in infant formula. Palm olein is also a more processed version of the original palm oil.

Learn more: Palm Oil in Baby Formula

Probiotics and Prebiotics

Similac Pure Bliss: Includes galactooligosaccharides as prebiotic, supporting gut bacteria growth for digestion and immunity.

Enfamil Enspire: Contains galactooligosaccharides, polydextrose as prebiotics, and probiotics. Combined, they promote a balanced gut ecosystem for better digestion and immune support.

Probiotics and prebiotics play crucial roles in promoting a healthy gut environment in infants. They aid digestion and boost the immune system by supporting the growth of beneficial bacteria in the gut.

Similac Pure Bliss includes galactooligosaccharides as a prebiotic in their formula. Prebiotics are a type of fiber that feed the friendly bacteria in your baby’s gut, stimulating their growth and dominance, thus leading to better digestion and immunity.

Enfamil Enspire, on the other hand, has both prebiotics (galactooligosaccharides and polydextrose) and probiotics in its formulation. This combination of probiotics and prebiotics can be more beneficial in promoting gut health, as they work together to ensure an optimal balance of good bacteria in your baby’s digestive system.

Best Places to Buy Similac Pure Bliss and Enfamil Enspire

Target-Logo
Walmart-Logo

Similac Pure Bliss

Buy Similac Pure Bliss at Target

Buy Similac Pure Bliss at Walmart

Enfamil Enspire

Buy Enfamil Enspire at Target 

Buy Enfamil Enspire at Walmart

What are the best alternatives to Similac Pure Bliss and Enfamil Enspire?

Even though Pure Bliss and Enspire are high-quality formulas, there are better options that you should consider before deciding.

Here are out favorite options:

  • Kendamil Organic: Our favorite formula for its organic certification. Kendamil Organic stands out for using whole milk instead of skimmed milk and includes real Human Milk Oligosaccharides (HMOs) from natural breast milk. HMOs are the third most abundant solid in breast milk and skilled at boosting baby’s growing immune system.

  • Bobbie: Our top US formula for its simplicity. Bobbie sets itself apart with its short and readable list of ingredients. If you have a preference for purity and minimally processed formulas, Bobbie may be the formula for you.

  • Hipp: Our best pick for babies with digestive issues such as reflux, allergies, or lactose sensitivities. Hipp has specific formulas designed to alleviate such problems and is recognized among parents for its gentle formulation.

Remember: Every baby is unique. Choosing the right baby formula involves finding what agrees best with your child’s tummy and meets their nutrition needs.

Last Words

We hope this comparison between Similac Pure Bliss and Enfamil Enspire helps you make an informed decision.

We encourage you to learn more about the alternatives above before making your final decision.

Remember, each baby is different, and what works with one might not work for another.

Happy feeding!

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