Key Differences Table Between Neosure and Advance
| Features/Aspect | Similac NeoSure | Similac Advance |
|---|---|---|
| Designed For | Preemies (premature babies) | Full-term babies |
| Key Nutrients | Extra calories, increased vitamins and minerals, enhanced protein | Well-rounded nutrition with DHA and ARA, prebiotics |
| Protein Content | Higher protein (2.8 grams per 100 calories) | Balanced protein (2.07 grams per 100 calories), whey-dominant |
| Carbohydrate Source | Lactose and corn syrup solids | Primarily lactose |
| Fats and Oils | Blend of coconut, soy, and high oleic sunflower oils | Blend of coconut, soy, and high oleic sunflower oils |
| Special Features | Tailored for rapid growth, more vitamins & minerals, DHA and ARA | DHA and ARA for brain and eye health, GOS prebiotics for digestion |
| Caloric Density | Higher calories for energy and growth | Standard caloric density for full-term infants |
| Protein Source | Cow’s milk (whey and casein) | Cow’s milk (whey and casein) |
| Prebiotics/Probiotics | None | Contains Galactooligosaccharides (GOS) |
| Suitability | For preemies needing extra growth support | For healthy growth and development in full-term infants |
This article will compare two Similac Formulas: NeoSure and Advance.
We will analyze their nutritional information and ingredients to help you make an informed decision for your baby.
Let’s get after it!
Related read: Pediasure vs Similac
Our Short Answer
The decision between these two formulas will depend on your baby’s needs.
On paper, Advance has the advantage of not using Corn Syrup Solids.
However, Neosure is higher in protein and essential minerals such as vitamin A, calcium, potassium, niacin, vitamin B6, pantothenic acid, phosphorus and we could go on.
This is because Neosure is designed to be consumed by premature babies, whose nutritional needs are higher than newborns because they have not finished developing in the womb.
So, if your baby needs that extra boost, Neosure should be your choice.
If your baby is born fully developed, then Advance is your best choice.
And you may wonder: wouldn’t it be better to offer Neosure to any baby, since it has more protein, vitamins and minerals?
The answer is no, because a fully developed baby does not have the capacity to absorb that amount of nutrients. Too much protein can be harmful to the kidneys, so don’t worry, leave Neosure for premature infants.
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Overview of the Two Formulas
Neosure is tailored for preemies, offering extra calories, increased vitamins and minerals, and enhanced protein for optimal growth and development.
Advance, ideal for full-term babies, provides well-rounded nutrition, including DHA and ARA for brain and eye health, and prebiotics for digestive well-being.
Neosure
Neosure is a unique formula for babies who decided to come into the world a bit early. These little champs, known as preemies, might need an extra nudge to catch up on growing big and strong. Here’s what makes Neosure unique:
- Extra Calories: More calories mean more energy for our tiny friends to grow.
- More Vitamins and Minerals: Imagine a teeny backpack full of all the good stuff needed for building strong bones and a clever brain. That’s what Neosure has inside.
- Protein Power: It’s like adding an extra scoop of muscle-building powder to help those little arms and legs get stronger.
Advance
This formula is for babies who are ready to take on the world right on schedule. It’s packed with good things that help babies who aren’t in a rush to get out and are born at the right time. Here’s what makes Advance awesome:
- Well-Rounded Nutrition: Think of Advance like a treasure chest filled with all the shiny nutrients babies need daily.
- DHA and ARA: These are like magic beans for the brain and eyes, helping your little one to see and think as sharp as a tack.
- Prebiotics for Happy Tummies: It’s like a friendly garden party in your baby’s belly, where good bacteria can dance and help digestion.
Nutritional Composition
Neosure provides higher protein and a blend of lactose and corn syrup solids for rapid growth in preemies, with a richer fat mix for extra energy.
Advance offers balanced protein primarily from lactose, ideal for full-term babies, and smart fats mimicking breast milk.
Both feature a blend of coconut, soy, and high oleic sunflower oils, along with DHA and ARA.
Protein Content
Protein in baby formula is like the building blocks in a giant Lego set. It’s what babies need to stack up muscles, cute chubby cheeks, and everything else!
Neosure:
- Higher Protein: Neosure is like the double-decker bus of proteins; it’s got more levels because preemie babies need more to build their tiny bodies.
- Whey and Casein: These proteins are from cow’s milk. They go hand in hand, like cookies and milk, to make a great team for growth.
Advance:
- Balanced Protein: Advance has a protein mix for full-term babies to keep them growing perfectly.
- Whey-Dominant: This formula leans more on whey, a gentler protein that’s easier to digest.
For reference, Neosure has 2.8 grams of protein per 100 calories, while Advance has 2.07. This is a very significant difference, and it’s normal because Neosure is designed for babies that need to grow extra fast in a shorter period of time.
Carbohydrate Content
Carbohydrates in formula are like the fuel in a race car. It keeps the engine humming and the wheels turning so that your baby has energy to laugh, cry, and play peek-a-boo!
Neosure:
- Special Carbs: For preemies, Neosure offers a special blend of carbs that’s easy to digest and helps them gain weight like little champs.
- Lactose and Corn Syrup Solids: This combo is like a dynamic duo, supporting development while being tummy-friendly.
Advance:
- Balanced Carbs: Advance packs a perfect balance of carbs for babies that aren’t racing to catch up.
- Mostly Lactose: Lactose is the major carbohydrate here, helping mimic mommy’s milk, which is the natural favorite of most tiny tummies.
Neosure uses corn syrup solids apart from lactose. This is to provide the baby with fast-digesting and high-calorie carbs. Lactose is typically the best carbohydrate for babies since it’s in breast milk. However, sometimes, the use of alternatives can provide benefits for some babies who have issues digesting lactose.
Fats and Oils
Fats and oils in baby formula are like the invisible force field around superheroes. They keep their tiny cells safe, help brains develop, and ensure every smile is shiny and healthy!
Neosure:
- Extra Rich Fats: Neosure has a bit more fat because preemie babies need all the energy they can get. It’s like adding an extra scoop of ice cream to their favorite dessert.
- Blend of Oils: A mix including coconut, soy, and high oleic sunflower oils ensures the babies get a wide range of fat heroes to protect them.
Advance:
- Smart Fats: The fat content in Advance is designed to be like what naturally comes from breastfeeding moms, making it a smart choice for optimal development.
- Special Oils: It’s got a mix of soy, coconut, and high oleic sunflower oils, creating a nutritious force field that’s wonderfully balanced.
Both fat blends are the same in the formulas. No differences.
Prebiotics and Probiotics
Neosure focuses on essential nutrients for growth and muscle development in infants but lacks prebiotics or probiotics.
Advance includes Galactooligosaccharides (GOS) as a prebiotic, promoting digestive health by nurturing beneficial gut bacteria.
Prebiotics and probiotics are becoming more popular in infant formulas thanks to their potential benefits to the babies microbiota. However, not every formula adds them for different reasons.
Neosure Neosure is designed to promote infant growth and muscle development but does not contain prebiotics or probiotics. Instead, it focuses on providing essential nutrients that support overall infant health.
Advance Advance is formulated with Galactooligosaccharides (GOS) as its primary prebiotic component. This ingredient aids in digestive health by supporting beneficial gut bacteria.
Best Places to Buy Neosure and Advance
Neosure
Advance
What are the Best Alternatives to Neosure and Advance?
Alternatives to Neosure
- Enfacare from Enfamil: If Neosure isn’t on the shelf, Enfacare steps in like a friendly neighbor. It’s also designed for premieres. *Read: Enfacare vs Neosure
Alternatives to Advance
- Kendamil: Picture Kendamil as the British cousin with a posh accent. It’s our favorite formula because it’s full of whole milk goodness and Omega-3s, giving your baby the royal treatment. *Read: Kendamil vs Similac
- Bobbie: If you’re looking for a homegrown superstar, Bobbie is the best U.S. brand that tips its hat to European standards, offering a formula that’s both organic and designed to mimic breastmilk closely. *Read: Bobbie vs Similac
- Hipp: For the little ones who are more delicate or have sensitive tummies, Hipp is like the gentle fairy godmother of formulas, packed with nutrients and made with care to reduce the chances of reactions. *Read: Hipp vs Similac
Last Words
We hope this comparison between Similac Neosure and Similac Advance helps you make the best decision for your baby. Remember that if you have any questions, you can contact us and we will help you in any way we can.
Happy feeding!
We’re Maria and Alberto, a married couple and educators who are nutrition enthusiasts. Even before we had kids, we were already crazy about nutrition.
We’d read scientific articles, watch videos from nutritionists, and spend hours listening to nutrition podcasts.
Today, we continue doing this, but in a different way, as we’ve learned to sift through the noise and trends. Nutrition, like any other field of knowledge, the more you read and learn, the more you develop a comprehensive understanding of reality, and that’s what has happened to us.
Before having our first child, we focused on learning everything we could about child nutrition, using the same techniques we had already employed, backed by our extensive knowledge in nutrition.
Our mission is to help other parents with their children’s nutrition, to help them become the best versions of themselves.
If we are what we eat and drink, which is absolutely true, let’s do it right!
