Key Differences Between Enfamil Neuropro and Similac Pro-Advance
| Enfamil Neuropro | Similac Pro-Advance | |
|---|---|---|
| Formula Type | Non-GMO, gluten-free, milk-based | Non-GMO, gluten-free, milk-based |
| Protein Source | Nonfat milk and whey protein concentrate (2g per 5 fl oz) | Nonfat milk and whey protein concentrate (2.07g per 5 fl oz) |
| Carb Source | Nonfat milk and lactose (11.3g per 5 fl oz) | Nonfat milk and lactose (10.5g per 5 fl oz) |
| Fat Source | Palm olein, coconut, soy, high oleic sunflower oils, Mortierella Alpina oil, Schizochytrium Sp. oil (5.3g per 5 fl oz) | High oleic safflower oil, soy oil, coconut oil, Schizochytrium Sp. oil, M. Alpina oil (5.6g per 5 fl oz) |
| Probiotics/Prebiotics | Triple prebiotic blend | 2′-FL HMO and Fructooligosaccharides |
| Palm Oil | Yes | No |
| Alternatives | Kendamil Organic, Bobbie, Holle | Kendamil Organic, Bobbie, Holle |
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This article compares two US popular formulas, Enfamil Neuropro vs Similac Pro-Advance, to give you the information you need to make an informed decision.
We will also share our professional opinions and personal beliefs and choose the one we would give our baby.
Let’s get after it!
*Related reads: Similac 360 Total Care vs Pro-Advance | Enfamil Gentlease vs Similac Pro-Advance
Our Short Answer
If we had to choose between Neuropro and Pro-Advance, we would choose the latter.
Although Neuropro has a more appropriate whey-to-casein ratio and MFGM: a very beneficial fatty acid, the inclusion of palm olein in its formula, along with the fact that Pro Advance adds 2′-FL HMO, a prebiotic found in breast milk, makes Pro Advance the formula we would personally choose for our baby.
That said, we always recommend exploring other organic alternatives such as Kendamil, Bobbie or Holle, our three favorite formula brands.
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Overview of the Two Formulas
Enfamil Neuropro is a pediatrician-recommended, non-GMO, and gluten-free formula.
Similac Pro-Advance focuses on immune health, brain and eye development, non-GMO, and calcium absorption with its unique components.
Enfamil Neuropro
Enfamil Neuropro is a pediatrician-recommended formula brand; it’s a milk-based, iron-fortified formula for infants aged 0-12 months. Certified non-GMO and gluten-free, it ensures safety and suitability for all babies.
Enfamil Neuropro boosts your baby’s overall development with its fat-protein blend enriched with MFGM (Milk Fat Globule Membrane) and Omega 3 DHA, previously found exclusively in breast milk. This blend has been clinically shown to foster cognitive development and immune support.
This formula leaps ahead by including a triple prebiotic blend focused on immune health, aligning with expert recommendations.
Similac Pro-Advance
Similac Pro-Advance is another promising formula offering complete nutrition to strengthen your baby’s immune system. With its unique 2′-FL HMO prebiotic, it makes strides to be as close to breast milk as possible.
It features an exclusive blend of DHA, lutein, and vitamin E, crucial components found in breast milk that support baby’s brain and eye development.
Similac Pro-Advance also stands out with its NO Palm Olein Oil formula for excellent calcium absorption, promoting strong bones for your little one.
Nutritional Composition
Enfamil Neuropro and Similac Pro-Advance have similar protein and carbohydrate content.
Enfamil Neuropro has a closer whey-to-casein ratio, while Similac Pro-Advance has higher casein.
Similac Pro-Advance wins in fat content by not using palm olein.
Both formulas include DHA and ARA.
Protein Content
Enfamil Neuropro and Similac Pro Advance pay great attention to their protein content, as it is a building block for your baby’s muscles.
Enfamil Neuropro: This formula uses nonfat milk and whey protein concentrate, providing 2g of protein per 5 fl oz serving.
Similac Pro Advance: Similac Pro Advance also uses nonfat milk and whey protein concentrate, ensuring an equivalent of 2.07g per 5 fl oz serving.
Both formulas have the same protein sources but differ in their whey-to-casein ratios.
Enfamil Neuropro has a 60:40, the optimal range and closes to breastmilk.
Similac Pro-Advance has a 48:52 ratio, which has higher amounts of casein.
The difference here is that whey protein is digested faster and easier. Casein protein stays in the stomach for longer periods of time, making the baby feel fuller for longer periods of time, but it may be a bit more difficult to digest for some babies.
Carbohydrate Content
Carbohydrates provide energy that supports babies’ expected growth and development.
Enfamil Neuropro: The main carbohydrate sources in this formula are nonfat milk and lactose, offering 11.3g of carbohydrates per 5 fl oz serving.
Similac Pro Advance: This formula uses nonfat milk and lactose for carbohydrates, delivering slightly fewer carbs at 10.5g per 5 fl oz serving.
It’s a draw in carbohydrate content, with both formulas using lactose exclusively. No added starches, corn syrups or maltodextrin.
This is exactly what we want to see in conventional formulas.
Fats and Oils
Fats in infant formulas play a crucial role in brain development and are a significant energy source.
Enfamil Neuropro: It contains a blend of vegetable oil (Palm Olein, Coconut, Soy, and High Oleic Sunflower Oils), Mortierella Alpina oil, and Schizochytrium Sp. oil in its fat content. These sources provide essential fatty acids, with a total fat content of 5.3g per 5 fl oz serving.
Similac Pro Advance: High Oleic Safflower Oil, Soy Oil, and Coconut Oil are the primary fat sources, along with additional DHA and ARA from Schizochytrium Sp. oil and M. Alpina oil. It has a slightly higher fat content, providing 5.6g per 5 fl oz serving.
Similac Pro Advance wins in fat content for the simple fact of not using palm olein like Neuropro.
Even though palm olein is safe for consumption, it’s a controversial ingredient for its environmental impact and being linked with bad calcium absorption.
Both formulas have sources of DHA and ARA.
Probiotics and Prebiotics
Both Enfamil Neuropro and Similac Pro-Advance include prebiotics for healthy gut microflora.
nfamil has a triple prebiotic blend for immune health, while Similac uses 2′-FL HMO and Fructooligosaccharides for immune and gut health.
Both Enfamil Neuropro and Similac Pro Advance offer the added bonus of prebiotics, fostering a healthy gut microflora that benefits your baby’s overall health.
Enfamil Neuropro enjoys the distinction of having a triple prebiotic blend, with a focus on immune health. This blend aims to mirror the function of prebiotics found in human milk, improving your baby’s digestive health.
Similac Pro Advance utilizes 2′-FL HMO, a breast milk prebiotic that fosters immune solid support. Also included are short-chain Fructooligosaccharides to help nourish the beneficial bacteria in your baby’s gut, promoting overall gut health.
Best Places to Buy Enfamil Neuropro and Similac Pro-Advance
Enfamil Neuropro
Similac Pro-Advance
Buy Similac Pro-Advance at Target
Buy Similac Pro-Advance at Walmart
What are the best alternatives to Enfamil Neuropro and Similac Pro-Advance?
Kendamil Organic: This is our favorite for its clean ingredient list. It uses whole milk, offering your baby a more natural and nutritious fat source. Additionally, it includes HMOs, a prebiotic found in breast milk, optimizing digestive health. *Read: Kendamil vs Similac | Kendamil vs Enfamil
Bobbie: Our selected US brand of choice is Bobbie, known for its simplicity and EU-inspired formula. Free from unnecessary additives, its formula contains everything your baby needs and nothing they don’t, making it a trusted option for discerning parents. *Read: Bobbie vs Similac Pro-Advance | Bobbie vs Enfamil
Holle: Holle should be on your radar if you’re looking for a formula sourced from organic farming methods. The German-based brand offers a range of formulas made from organic goat’s or cow’s milk, providing natural and wholesome ingredients for your baby. *Read: Holle vs Similac | Holle vs Enfamil
Last Words
We hope this comparison between Enfamil Neuropro and Similac Pro-Advance has helped you make an informed decision for your baby.
We strongly recommend you check out the abovementioned alternatives since offering Organic Formulas is always a better option during the first year.
See you around!
We’re Maria and Alberto, a married couple and educators who are nutrition enthusiasts. Even before we had kids, we were already crazy about nutrition.
We’d read scientific articles, watch videos from nutritionists, and spend hours listening to nutrition podcasts.
Today, we continue doing this, but in a different way, as we’ve learned to sift through the noise and trends. Nutrition, like any other field of knowledge, the more you read and learn, the more you develop a comprehensive understanding of reality, and that’s what has happened to us.
Before having our first child, we focused on learning everything we could about child nutrition, using the same techniques we had already employed, backed by our extensive knowledge in nutrition.
Our mission is to help other parents with their children’s nutrition, to help them become the best versions of themselves.
If we are what we eat and drink, which is absolutely true, let’s do it right!
