Enfamil-Neuropro-Gentlease-vs-Similac-Total-Comfort

Key Differences Between Enfamil Neuropro Gentlease and Similac Total Comfort

AspectEnfamil Neuropro GentleaseSimilac Total Comfort
Protein2.3g per serving, partially hydrolyzed nonfat milk and whey protein concentrate solids2.32g per serving, whey protein hydrolysate
Carbohydrates10.8g per serving, from corn syrup solids10.7g per serving, from corn maltodextrin and added sugar
Fats5.3g per serving, from a blend of vegetable oils including palm olein, soy, coconut, and high oleic sunflower oils, and MFGM5.4g per serving, from high oleic safflower oil, soy oil, and coconut oil
Prebiotics or ProbioticsNoneIncludes short-chain fructooligosaccharides (a prebiotic)
Key BenefitsReduces fussiness, supports brain development with MFGM, offers multiple packaging optionsDesigned for easy digestion and softer stools for sensitive tummies, includes OptiGRO for overall growth and development
Controversial IngredientsUses palm olein oilIncludes added sugar
Suggested AlternativesHipp HA, Hipp Comfort, Anti-Reflux, Kendamil, NannycareHipp HA, Hipp Comfort, Anti-Reflux, Kendamil, Nannycare

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This article aims to compare two popular sensitive formulas: Enfamil Neuropro Gentlease vs Similac Total Comfort.

We will analyze their ingredients and nutritional composition to help you make an informed decision.

Let’s let started!

*Related read: Enfamil Gentlease vs Similac Total Comfort

Our Short Answer: is similac total comfort the same as enfamil gentlease?

They are not the same, but are designed for babies with similar digestive needs.

In our comparison between Enfamil Neuropro Gentlease and Total Comfort, we choose Neuropro.

The Neuropro version of Gentlease adds a key ingredient: MFGM or Milk Fat Globule Membrane.

Including this ingredient makes us lean on this occasion towards Enfamil Neuropro Gentlease since many studies have demonstrated its cognitive, immunological, and nutritional benefits.

As always, we encourage you to read the entire article to be more informed and read about the alternatives we recommend below.

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Overview of the Two Formulas

Enfamil Neuropro Gentlease reduces fussiness, supports brain development, and offers convenient packaging options. Has palm olein, corn syrup solids, and MFGM.

Similac Total Comfort is designed for delicate tummies, with partially hydrolyzed protein, prebiotics, and OptiGRO for overall growth and development.

Enfamil Neuropro Gentlease

Enfamil Neuropro Gentlease’s primary selling point is its proven ability to reduce fussiness, gas, crying, and spit-up within 24 hours of use. It also supports brain development by including Omega 3 DHA in recommended amounts by global experts.

This infant formula comes in powder and liquid forms in various packaging options.

Whether you prefer a tub or bottle format or need a compact pack for when you’re on the go, there’s likely an option that’ll suit your needs.

Moreover, this formula offers complete nutrition for babies through 12 months. It contains easy-to-digest proteins and essential vitamins and minerals relevant to immune health – all carefully measured to ensure your little one gets maximum nutritional value from each serving.

Similac Total Comfort

On the other hand, we have Similac Total Comfort – equally lauded by parents worldwide due to its composition explicitly tailored for delicate tummies.

This baby formula has partially hydrolyzed protein which makes digestion easier.

Interestingly enough, it also incorporates prebiotics which promote a healthier guy for a lot of babies.

Similac Total Comfort prides itself on containing OptiGRO – their exclusive blend of DHA, Lutein and Vitamin E; nutrients crucial in supporting overall growth and brain, eye, and immune system development in babies.

Nutritional Composition

Neuropro Gentlease uses partially hydrolyzed nonfat milk and whey protein concentrate solids, while Total Comfort uses partially hydrolyzed whey protein as well.

Neuropro Gentlease uses corn syrup solids as its carbohydrate source, while Total Comfort uses corn maltodextrin and some sugar.

Both formulas have similar fat content, but Neuropro Gentlease includes palm olein (not good) and MFGM (very good).

Protein Content

The protein content is basically the same between both formulas, with Enfamil Gentlease and Similac Total Comfort containing 2.3g and 2.32g of protein per 100 Calories, respectively.

In terms of sources, Enfamil NeuroPro Gentlease derives its protein from partially hydrolyzed nonfat milk and whey protein concentrate solids, making it easier to digest.

Similac Total Comfort uses whey protein hydrolysate as its source – a form of pre-digested or partially broken down protein designed to be easy on little tummies, especially for infants with digestion issues.

Both formulas share the same approach to protein, using partially hydrolyzed milk. This means it is easier to digest because it has been partially broken down.

Important note: If your baby has been diagnosed with CMPA or cow’s milk protein allergy, you should acquire an extensively hydrolyzed formula. Always check with your pediatrician.

*Learn more: Partially vs Extensively Hydrolyzed formulas

Carbohydrate Content

Regarding carbohydrates, there are slight differences in quantity but significantly more in sources across the two formulas. For every 100 Calorie serving, Enfamil NeuroPro Gentlease provides roughly 10.8 grams of carbohydrates, while Similac Total Comfort delivers around 10.7 grams.

Enfamil Neuropro Gentlease primarily uses corn syrup solids as its carbohydrate source which can easily supply the energy that your baby needs throughout the day.

Similac Total Comfort’s formula opts for corn maltodextrin and some sugar.

While corn maltodextrin is a better choice than corn syrup solids a priori (giving Similac Total Comfort an advantage), the fact that Total Comfort adds a little sugar makes it a tie.

Both corn maltodextrin and corn syrup solids are acceptable alternatives to lactose for these formulas, designed for infants with digestive problems.

Fats and Oils

Enfamil Neuropro Gentlease contains around 5.3 grams, while Similac Total Comfort contains approximately 5.4 grams per serving size.

The fats used in Enfamil NeuroPro Gentlease come from a blend of vegetable oils, including palm olein, coconut, soy, high oleic sunflower oils.

Neuropro Gentlease also includes MFGM (Milk Fat Globule Membrane) — a research-backed component believed to bring the formula’s fat profile closer to breast milk while contributing positively towards cognitive development and overall immunity.

On the other hand, Similac Total Comfort uses high oleic safflower, soy, and coconut oil for its fat sources. 

Enfamil Neuropro Gentlease adds palm olein to its formula, a more processed version of palm oil. It is a controversial ingredient as some studies have seen conflicts with calcium absorption, apart from the usual problems at the environmental level.

Despite this, Neuropro Gentlease adds an ingredient that we believe is key: MFGM. This puts it above Similac Total Comfort in our eyes, even though Total Comfort does not add palm oil or palm olein to its formula.

Probiotics and Prebiotics

Enfamil NeuroPro Gentlease does not include probiotics or prebiotics, while Similac Total Comfort contains prebiotics.

Enfamil NeuroPro Gentlease does not feature probiotics or prebiotics in its formulation, while Similac Total Comfort includes prebiotics, more specifically Short-Chain Fructooligosaccharides.

Even though these components are not necessary ingredients in baby formulas, they can potentially benefit some babies.

Prebiotics and probiotics support microbiota balance and overall gut health.

They promote healthy digestion by keeping harmful bacteria at bay while nourishing beneficial gut bacteria.

It is always important to discuss these factors with a healthcare provider if your baby has sensitivities.

Best Places to Buy Enfamil Neuropro Gentlease and Similac Total Comfort

Target-Logo
Walmart-Logo

Enfamil Neuropro Gentlease 

Buy Enfamil Gentlease at Target

Buy Enfamil Gentlease at Walmart

Similac Total Comfort 

Buy Similac Total Comfort at Target

Buy Similac Total Comfort at Walmart

What are the best alternatives to Neuropro Gentlease and Total Comfort?

We would consider other formulas before going for Enfamil and Similac.

Here are our recommendations:

  • Hipp Comfort and Anti-Reflux: These are ideal substitutes if your baby has lactose sensitivity or reflux issues respectively, as they’re specially formulated with such conditions in mind. *Read: Hipp Anti-Reflux vs Comfort

  • Hipp HA: This organic hypoallergenic formula works excellently for babies susceptible to allergies due to its compositionally optimized design endorsing minimized allergic responses. *Read: Hipp HA vs Gentlease

  • For infants struggling with cow’s milk protein digestion without Cow Milk Protein Allergy (CMPA), goat milk formulas like Kendamil or Nannycare could be beneficial alternatives. They offer relatively easier digestibility and a healthier nutrient profile, encapsulating a wide array of essential nutrients to effectively cater to full-spectrum infant nutritional requirements. Additionally, they are gentler on their tummies. *Read: Nannycare vs Kendamil Goat

Last Words

We sincerely hope this comparison between Enfamil Neuropro Gentlease and Similac Total Comfort has helped you make an informed decision.

We recommend you read about the alternatives before making any purchasing decisions just in case you find a better option for your baby.

If you have further questions, we’ll be happy to help you, just leave a comment, and we’ll get back to you in less than 24 hours.

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