Enfamil-Neuropro-Gentlease-vs-Similac-Sensitive

Key Differences Between Enfamil Neuropro Gentlease and Similac Sensitive

 Enfamil Neuropro GentleaseSimilac Sensitive
ProteinPartly broken down (easier to digest) ✔Not broken down (harder to digest) ❌
CarbohydratesCorn Syrup Solids (No added sugars) ✔Corn Syrup and Sugar blend (added sugar) ❌
Fats & OilsUses palm olein but has a better DHA source ✔Does not use palm olein but DHA source is not as good ❌
Probiotics & PrebioticsNone ❌None ❌
DigestibilityEasier for babies with cow’s milk digestion issues and lactose sensitivities ✔Only for lactose sensitive babies ❌
Palm OleinUses Palm Olein ❌Does not use Palm Olein ✔
MFGMIncluded (Beneficial for cognitive development and immune support) ✔Not Included ❌
Best AlternativesHipp HA, Hipp Comfort, Hipp Anti-RefluxHipp HA, Hipp Comfort, Hipp Anti-Reflux
⭐ OverallPreferred due to better protein, no added sugars, better DHA source, inclusion of MFGM ✔Good, but not as preferred due to harder to digest protein, added sugar, less ideal DHA source ❌

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This article will compare two popular formulas for sensitive tummies: Enfamil Neuropro Gentlease vs Similac Sensitive.

We will analyze their ingredients and nutritional composition to provide you with the information you need to make an informed decision.

Let’s get started!

Related read: Enfamil Gentlease vs Similac Sensitive

Our Short Answer

The clear winner is Enfamil Neuropro Gentlease, for the following reasons:

1. It uses partially hydrolyzed protein (easier to digest) 
2. Both formulas use Corn Syrup Solids, but Enfamil does not add extra added sugars.
3. It has a more natural and concentrated DHA source.
4. Adds MFGM, or Milk Fat Globule Membrane, an ingredient found in breast milk that is highly beneficial for babies.

That said, if your baby has a cow’s milk protein allergy (CMPA), none of these formulas are suitable, and you will need to look for a formula that is extensively hydrolyzed.

Read: Best Hypoallergenic Formulas

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Overview of the Two Formulas

Enfamil Neuropro Gentlease

Enfamil NeuroPro Gentlease is a scientifically designed infant formula that claims to reduce fussiness, crying, gas, and spit-up within 24 hours of use.

It offers a mix of easy-to-digest proteins and vitamins and minerals essential for immune health.

Infused with brain-building Omega-3 DHA in an amount recommended by global experts, this formula aims to support cognitive development and physical growth.

It offers complete nutrition for babies through 12 months and is available in powder and liquid forms.

Similac Sensitive

Similac Sensitive is another renowned option for babies with sensitive tummies due to lactose sensitivity. It targets common discomforts like gas or mild spit-up and provides complete nutrition for your child.

This formula includes DHA and lutein — important ingredients found in breast milk that support brain and eye development. Moreover, it contains no palm olein oil, which improves calcium absorption.

Furthermore, it’s gluten-free, making it a suitable option if you prefer your baby’s diet to be devoid of gluten elements.

Nutritional Composition

Enfamil Neuropro Gentlease uses partially hydrolyzed nonfat milk and whey protein concentrate solids as its protein source, while Similac Sensitive uses Milk Protein Isolate. 

Both formulas use corn syrup solids as the carbohydrate source, but Similac Sensitive includes added sugar.

Enfamil uses a blend of vegetable oils, including palm olein, while Similac Sensitive uses high oleic safflower, soy, and coconut oil.

Enfamil includes MFGM, which has benefits for cognitive development and immune support.

Protein Content

In Enfamil Neuropro Gentlease, the protein source is partially hydrolyzed nonfat milk and whey protein concentrate solids. Partially hydrolyzed proteins are easier to digest, lessening the chances of fussiness, gas, or upset stomach. In 5 fl oz serving (normal dilution) it provides 2.3g of protein.

Similac Sensitive uses Milk Protein Isolate as its primary protein source. It offers slightly less protein content compared to Enfamil Neuropro Gentlease with 2.1g per 5 fl oz serving prepared as directed.

There is a significant difference in protein content. 

Enfamil uses partially hydrolyzed protein, designed for babies with problems digesting cow’s milk protein.

Similac Sensitive, however, uses protein isolate, which is unsuitable for babies with that problem.

*Learn more: Hydrolyzed Infant Formulas

Carbohydrate Content

Enfamil Neuropro Gentlease uses corn syrup solids as its primary carbohydrate source, providing 10.8g per 100 calories (5 fl oz) serving size.

Similac Sensitive also uses corn syrup and added sugar as the primary carbohydrate sources, with a slightly higher amount than its counterpart at 10.9g per 5 fl oz serving prepared as directed.

Both formulas are suitable for babies with lactose sensitivities or intolerances.

Enfamil comes on top because Similac Sensitive adds extra sugar on top of the corn syrup solids, which only makes the formula sweeter.

As parents, it is always better to aim to get formulas with neutral flavors.

Fats and Oils

Enfamil Neuropro Gentlease leverages Vegetable Oil (Palm Olein, Coconut, Soy, And High Oleic Sunflower Oils) for its fat source. It contains Omega-3 DHA and ARA from Mortierella Alpina Oil and Schizochytrium Sp. Oil which are essential fats every baby needs for brain and eye development. In terms of quantity, it provides approximately 5.3 grams per 100 calories (5 fl oz).

Similac Sensitive utilizes an array of oils: High Oleic Safflower Oil, Soy Oil, Coconut Oil including C.Cohnii oil which is a source of DHA and M.Alpina oil – a source of ARA (both also Omega-3 fatty acids). These sources provide around 5.4 grams per each 100-calorie serving size (around 5 oz).

Even though Enfamil Neuropro Gentlease uses palm olein (which is a more processed version of palm oil, a pretty controversial ingredient – you can learn more here), it is still ahead of is competitor in our eyes.

This is because it uses Schizochytrium Sp. Oil instead of C.Cohnii oil, which is a better DHA source, more concentrated and environmentally friendly. 

Vitamins, Minerals, and Other Ingredients

Enfamil Neuropro Gentlease and Similac Sensitive baby formulas contain all the essential vitamins and minerals for your baby’s development.

These include vitamins A, D, E, B1, B2, B6, B12, Niacin, Folic acid, Pantothenic Acid, and Biotin. The mineral content includes essential nutrients in the right quantities such as Calcium, Phosphorus, Iron, and Zinc.

The main difference here is the fact that Enfamil Neuropro Gentlease includes MFGM or Milk Fat Globule Membrane, a highly beneficial ingredient with the following qualities:

  • Supports cognitive development: MFGM (Milk Fat Globule Membrane) is found in breast milk and plays an important role in brain structure and function. Supplementation of MFGM in infant formula has been shown to support cognitive development similar to breast milk 
  • Boosts immunity: MFGM contains compounds that are rich in antiviral and antimicrobial mechanisms, helping to build the body’s immunity and strengthen defense against infections 
  • Reduces the risk of acute otitis media: Supplementation of infant formula with MFGM has been shown to reduce the risk of acute otitis media, a painful ear infection that occurs in infants 
  • Promotes healthy intestinal development: MFGM supplementation in infant formula has been found to have positive effects on intestinal development and protect against harmful toxins, which is especially important for vulnerable populations such as premature infants 
  • Decreases incidence of bloody diarrhea: Infants receiving formula supplemented with MFGM have shown a reduced occurrence of bloody diarrhea 
  • Enhances immune response to vaccines: MFGM supplementation in infant formula has been found to have immune-modulatory effects on the humoral response against the pneumococcus vaccine. 

Probiotics and Prebiotics

Prebiotics and probiotics are not essential ingredients in infant formula, but they may benefit some babies.

Neither of the two formulas has prebiotics or probiotics.

Probiotics and prebiotics in baby formula can help promote a healthier gut microbiome for your little one, but they are not essential ingredients.

They are commonly found in various infant formulas on the market today.

However, neither Enfamil Neuropro Gentlease nor Similac Sensitive include these beneficial bacteria or its food sources in their formulation.

While both these formulas offer many beneficial ingredients designed to replicate breast milk as closely as possible, the absence of probiotics and prebiotics may be a factor to consider for some parents. 

Best Places to Buy Enfamil Neuropro Gentlease and Similac Sensitive

Target-Logo
Walmart-Logo

Enfamil Neuropro Gentlease 

Buy Enfamil Gentlease at Target

Buy Enfamil Gentlease at Walmart

Similac Sensitive 

Buy Similac Sensitive at Target 

Buy Similac Sensitive at Walmart

What are the best alternatives to Enfamil Neuropro Gentlease and Similac Sensitive?

There are other formulas in the market that are better in our opinion for sensitive tummies. Here you have our recommendations.

  1. Hipp HA: This option stands out for its organic ingredients and the inclusion of both a prebiotic and probiotic blend for your baby’s gut health. Plus, it contains hydrolyzed proteins that are easier for babies to digest—the brand’s commitment to organic sets it apart from others on the market. *Read: Hipp HA vs Enfamil Gentlease

  2. Hipp Comfort: Specifically designed for infants with digestion issues, this formula has reduced lactose content. If your baby has lactose sensitivity, this formula is a great option.

  3. Hipp Anti-Reflux: This formula is tailored for babies experiencing reflux issues. Its unique component, organic locust bean gum, helps thicken the formula, reducing the chances of acid reflux or spitting up. *Read: Hipp Comfort vs Anti-Reflux

Last Words

We hope this comparison between Enfamil Neuropro Gentlease and Similac Sensitive has helped you make an informed decision.

We still recommend you do some reading about the alternatives above before you make a purchasing decision.

If you have further questions, we’ll be happy to help you, just leave a comment below and we’ll get back to you in less than a day.

See you around!

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