Enfamil-Neuropro-Gentlease-vs-Similac-Pro-Sensitive

Key Differences Between Enfamil Neuropro Gentlease and Similac Pro-Sensitive

 Enfamil Neuropro GentleaseSimilac Pro-Sensitive
Milk SourcePartly Hydrolyzed MilkMilk Protein Isolate
CarbohydratesCorn Syrup SolidsCorn Syrup Solids + extra sugar
Fat & Oil ContentContains Palm Olein, MFGMNo Palm Olein
Cognitive DevelopmentDHA, MFGMDHA, Lutein, Vitamin E
Prebiotics/ProbioticsNot SpecifiedContains 2â€Č-FL HMO prebiotic
⭐ Overall RecommendationFirst choice due to presence of MFGMHealthier fat profile and presence of prebiotic

Blwstore is supported by its audience. When you buy through links on our site, we may earn an affiliate commission.

It’s not easy to find the perfect formula for your baby. It’s even more difficult if you have to choose a high-quality sensitive formula for your baby’s tummy troubles.

This article will compare two popular sensitive formulas: Enfamil Neuropro Gentlease vs Similac Pro Sensitive.

We will analyze their ingredients and nutritional composition so you can make the best decision for your little one.

Let’s get after it!

*Related read: Enfamil Gentlease vs Similac Pro-Sensitive

Our Short Answer

In the previous comparison between the conventional version of Gentlease (No Neuropro) versus Pro-Sensitive, we chose the latter, but things get a little more complicated on this occasion.

Both formulas have their strengths and weaknesses.

Enfamil Neuropro Gentlease:
+ It has partially hydrolyzed milk.
+ It has MFGM (milk fat globule membrane).
– Has palm olein
– No prebiotics

Similac Pro-Sensitive:
+ No palm olein
+ Has 2′-FL HMO, one of the best prebiotics for babies.
– Adds added sugar
– No hydrolyzed milk

Considering these pros and cons, if we had to choose one for our baby, we would select Neuropro Enfamil Gentlease.

In our opinion, the fact that it includes MFGM is reason enough to give the win to Enfamil Neuropro Gentlease, taking into account the rest of the differences.

That said, we recommend looking at the alternatives in the article below. 


At BLWStore, we may earn a commission from some of the products featured on our website through affiliate partnerships with retailers. We want to be transparent with our readers and let you know that we do not receive any products for special consideration. The commission we earn helps support our website and allows us to continue providing helpful information and product recommendations. Thank you for your support!

Overview of the Two Formulas

Enfamil NeuroPro Gentlease reduces fussiness and includes Omega 3 DHA for brain development.

Similac Pro-Sensitive is for lactose sensitivity, includes 2′-FL HMO prebiotic for the immune system, and features lutein, DHA, and Vitamin E for brain and eye development. 

Enfamil Neuropro Gentlease

Enfamil NeuroPro Gentlease is a leading baby formula well-known for its effectiveness in reducing fussiness, gas, and spit-up within a mere 24 hours. This formula is beneficial for infants with sensitive stomachs and is a go-to choice for many parents.

Neuropro Gentlease boasts the presence of Omega 3 DHA, the amount experts globally recommend that helps brain building. 

This well-rounded formula provides sufficient nutrition for babies up to 12 months while being easy on their developing digestive system. It contains digestible proteins, immunity-boosting vitamins, and minerals.

The powder formula of Enfamil NeuroPro Gentlease comes in numerous size options and is available in powder and liquid forms.

Similac Pro-Sensitive

Similac Pro-Sensitive infant formula is another reputable option developed specifically for babies with sensitive tummies who experience fussiness and gas due to lactose sensitivity.

It stands out because it includes 2′-FL human milk oligosaccharide (2′-FL HMO), an immune-nourishing prebiotic similar to what occurs naturally in breast milk.

Another unique aspect of Similac Pro-Sensitive is its blend of lutein, DHA, and Vitamin E – critical factors that promote brain and eye development found in breast milk. Besides, this formula does not contain palm olein oil – facilitating better calcium absorption essential for strong bones!

Nutritional Composition

Enfamil Neuropro Gentlease and Similac Pro-Sensitive have similar protein content.

Enfamil uses partially hydrolyzed nonfat milk and whey protein concentrate solids, while Similac uses milk protein isolate.

Enfamil Neuropro Gentlease has a slightly lower carbohydrate content than Similac Pro-Sensitive.

Both formulas use corn syrup solids, but Similac adds extra sugar.

Enfamil includes MFGM for cognitive development in fat content, while Similac avoids palm olein oil.

Protein Content

Both Enfamil Neuropro Gentlease and Similac Pro-Sensitive fall closely when it comes to the protein content. Enfamil offers 2.3g of protein per 100 calories, while Similac contributes slightly less, with a protein amount of 2.1g per 100 calories.

Regarding the source, Enfamil Neuropro Gentlease derives its proteins predominantly from partially hydrolyzed nonfat milk and whey protein concentrate solids (soy)

Similac Pro-Sensitive obtains its proteins from milk protein isolate – a complete protein that contains all essential amino acids. 

Both formulas are quite different when it comes to their protein sources.

The fact that Enfamil Gentlease uses partially hydrolyzed milk protein, makes it easier to digest than normal milk protein. This is very helpful for those babies who have problems digesting cow’s milk protein.

Similac Pro-Sensitive uses Milk Protein Isolate, which technically is also easy to digest, but not as much as if it was hydrolyzed.

*Keep learning: Hydrolyzed formulas

Carbohydrate Content

As for carbohydrate content, both formulas offer much the same. Enfamil Neuropro Gentlease has 10.8g per 100 calories, whereas Similac Pro-Sensitive possesses slightly more with 10.9g per 100 calories.

Enfamil Neuropro Gentlease utilizes corn syrup solids as a fast energy source, which provide quick energy release and are easy to digest. 

Similac Pro-Sensitive uses a combination of corn syrup and sugar for its carbohydrate content. It offers a balanced blend of easily digested carbs that can provide instant and slow-releasing energy sources.

Corn syrup solids, which both formulas use, are a suitable alternative to lactose for those formulas designed for babies with problems digesting lactose; however, there are better options like organic maltodextrin or starches.

The fact that Similac Pro-Sensitive adds extra sugar on top of the already sweet and high-sugar corn syrup solids makes Enfamil Neuropro Gentlease the winner regarding carbs.

Fats and Oils

Optimal amounts of fats in baby formulas contribute significantly to necessary caloric intake, brain development, digestion, and vitamin absorption, amongst other functions.

When it comes to fat content, both Enfamil Neuropro Gentlease and Similac Pro-Sensitive contain around 5g (5.3g in Enfamil and 5.4g in Similac) per 100 calories serving.

The fats in the Enfamil Neuropro Gentlease formula come from vegetable oils, including palm olein, coconut oil, soy oil, high oleic sunflower oils, along with oils derived from Mortierella alpina (a source of Arachidonic Acid), and Schizochytrium sp.(a source of DHA). It also adds MFGM or Milk Fat Globule Membrane, a high-nutritious fat found in breast milk, very beneficial for babies.

Similac Pro-Sensitive’s fat sources include high oleic safflower oil, and soy oil, along with coconut oil similar to his counterpart option but also has sources like M.Alpina Oil(which is an ARA source)and Schizochytrium sp.oil(a DHA source).

Similac Pro-Sensitive should win the fat content battle, thanks to not having palm olein. (palm olein is a more processed form of palm oil)

Even though palm oil has its uses, we think it has to be organically grown to be added to baby formula.

*Learn more: Palm Oil in Baby Formula

However, Enfamil Neuropro adds MFGM, a naturally occurring membrane surrounding breast milk fat droplets. It is known to support a baby’s cognitive development. This ingredient easily gives Neuropro the win in fat content, even though it uses palm olein.

Probiotics and Prebiotics

Enfamil Neuropro Gentlease does not contain prebiotics or probiotics.

Similac Pro-Sensitive includes 2′-FL HMO prebiotic, beneficial for a baby’s microbiota.

Neither formula includes probiotics in their ingredients.

Including prebiotics and probiotics in baby formulas is not essential, but it could benefit some babies.

Enfamil Neuropro Gentlease does not have any pre or probiotic listed in their ingredient list and instead, it focuses on creating an easy to digest formula.

Similac Pro-Sensitive, however, does include 2’-FL HMO, a human milk oligosaccharide prebiotic (not from natural milk). This prebiotic is the best kind for a baby’s microbiota.

None of the formulas include probiotics in their ingredients.

Best Places to Buy Hipp HA and Gentlease

Target-Logo
Walmart-Logo

Enfamil Neuropro Gentlease 

Buy Enfamil Gentlease at Target 

Buy Enfamil Gentlease at Warlmart

Similac Pro-Sensitive 

Buy Similac Pro-Sensitive at Target 

Buy Similac Pro-Sensitive at Walmart

What are the best alternatives to Enfamil Neuropro Gentlease and Similac Pro-Sensitive?

There are other formulas out there that are more natural and more beneficial for your baby. Here are our recommendations:

  • Kabrita and Jovie (or other goat milk formulas): If your baby has sensitivities or digestive issues and cow’s milk formulas are not suitable, consider trying Kabrita and Jovie. Goat’s milk formulas are easier to digest than cow’s milk formulas. *Read: Kabrita vs Jovie

  • Hipp formulas: Known for their powerful blend of prebiotics and probiotics, Hipp formulas offer a great option for babies with sensitivities or digestive issues. They provide a distinctive choice for those seeking hypoallergenic baby formula with organic and pure ingredients. *Read: Hipp Comfort vs Anti-Reflux, Hipp HA vs Enfamil Gentlease

Last Words

We hope this comparison between Enfamil Neuropro Gentlease and Similac Pro-Sensitive has helped you make an informed decision for your baby.

We recommend you read about the alternatives above.

If you have further questions, please comment below or contact us, and we’ll get back to you in less than 24 hours.

See you around!

Similar Posts

Leave a Reply

Your email address will not be published. Required fields are marked *