Key Differences Table Between Gentlease and ProSobee
| Features/Aspect | Enfamil Gentlease | Enfamil ProSobee |
|---|---|---|
| Ideal For | Babies less than 12 months old with lactose and/or cow’s milk protein sensitivities | Babies 6 months or older (preferably 12 months), lactose intolerant or with CMPA |
| Type | Milk-based formula with partially hydrolyzed proteins | Soy-based, dairy-free formula |
| Primary Protein Source | Partially hydrolyzed nonfat milk and whey protein concentrate solids from soy | Soy protein isolate |
| Carbohydrate Source | Corn syrup solids | Corn syrup solids |
| Fats and Oils | Palm olein, soy, coconut, high oleic sunflower oils | Palm olein, coconut, soy, high oleic sunflower oils |
| Nutritional Support | Fortified with DHA, Triple Health Guard blend including 30 nutrients | Essential fatty acids, DHA for cognitive brain development |
| Ease of Digestion | Designed for easy digestion, suitable for fussiness, gas, or crying | Gentle on the stomach, suitable for lactose intolerance or milk allergies |
| Special Ingredients | NeuroPro version includes MFGM (Milk Fat Globule Membrane) | – |
| Suitability | Suitable for common sensitivities, not for severe allergies (CMPA) | Suitable for CMPA, lactose intolerance, vegetarian or Kosher diets |
| Prebiotics/Probiotics | None | None |
This article will compare two Enfamil formulas for sensitive babies: Enfamil Gentlease and Enfamil ProSobee.
We will analyze their ingredients and nutritional composition to help you make the best decision for your baby.
Let’s get after it!
***Important: Soy formulas are not recommended for infants younger than six months of age due to estrogen content and should not be used to treat CMPA until a pediatrician gives the okay.
Related read: Enfamil Sensitive vs Gentlease
Our Short Answer
There is no absolute winner in this comparison. The formula you choose will depend on your baby’s needs and situation.
Choose Enfamil Gentlease if:
- Your baby is less than 12 months old
- Has lactose and/or cow’s milk protein sensitivities
This often translates into colic, discomfort, constant vomiting… We recommend you choose Enfamil Neuropro Gentlease instead of the base option, as it adds MFGM (Milk Fat Globule Membrane), a highly beneficial ingredient for babies.
Choose Enfamil ProSobee if:
- Your baby is 6 months or older (although it is recommended that he/she has reached 12 months. Always consult a pediatrician before offering soy formulas).
- Your baby is lactose intolerant or has a cow’s milk protein allergy (CMPA).
Having said all this, we recommend you take a look at the alternatives below in the article, as there are better options on the market.
With over 100,000 orders delivered globally since 2019, Organic's Best offers clean, safe, and nutritionally rich formulas and snacks.
Free shipping over $100, commitment to freshness and authenticity.
- Express delivery in 2 to 5 business days
- Sourcing from European manufacturers
- Minimum shelf life of 6 months
- Climate-Controlled Warehouse
Give your little one the best start.
CODE 'BLW' for a 5% discount in all orders
Overview of the Two Formulas
Enfamil Gentlease uses partially hydrolyzed nonfat milk and whey protein from soy for easy digestion, ideal for fussiness and gas, with a nutrient-rich blend including DHA.
ProSobee is a soy-based, dairy-free formula suitable for lactose intolerance, vegetarians, or Kosher diets, also containing DHA for cognitive development.
Gentlease
Enfamil Gentlease is formulated to ease your baby’s sensitive tummy. It is a milk-based formula, but the key distinction lies in its protein content.
The formula features partially hydrolyzed nonfat milk and whey protein concentrate solids from soy, making the proteins smaller and easier to digest for infants. This can be especially beneficial for those little ones who struggle with fussiness, gas, or crying due to gastrointestinal discomfort.
A notable aspect of Gentlease is its Triple Health Guard blend, which includes 30 nutrients to support your infant’s growth during their first year. Additionally, it contains DHA—a fatty acid that plays a crucial role in cognitive development—helping maximize your child’s learning potential.
ProSobee
Enfamil ProSobee takes a different route—it’s a soy-based formula made without any lactose or dairy components, making it suitable for babies with lactose intolerance or families who follow vegetarian or Kosher diets.
This plant-sourced protein option contains soy protein isolate as the primary ingredient after corn syrup solids and vegetable oil.
ProSobee aims to alleviate issues like gas and colic that may stem from sensitivity to milk-based formulas. Like Gentlease, ProSobee includes essential fatty acids such as DHA for cognitive brain development, covering the nutrients needed during an infant’s critical early stages.
Nutritional Composition
Enfamil Gentlease uses partially hydrolyzed milk proteins for easier digestion in babies with sensitivities, while ProSobee offers soy protein isolate, suitable for lactose intolerance, milk allergies, or vegetarian diets.
Both have corn syrup solids as the primary carbohydrate, and identical fat blends, including palm olein, with added ARA and DHA.
Protein Content
Enfamil Gentlease: The protein source in Enfamil Gentlease derives from partially hydrolyzed nonfat milk and whey protein concentrate solids from soy. The hydrolyzation process breaks down the proteins into smaller pieces, which can be easier for babies to digest.
Enfamil ProSobee: In contrast, Enfamil ProSobee’s primary protein source is soy protein isolate. This plant-based protein is ideal for babies who require a dairy-free diet, including those with lactose intolerance or milk allergies. Soy protein isolate is also suitable for families seeking vegetarian nutritional options for their infants.
Enfamil Gentlease uses partially hydrolyzed skimmed milk and soy protein solids. This blend is suitable for babies with cow’s milk protein sensitivities since hydrolyzed protein is much easier to digest. However, it’s not suitable for babies with severe allergies (CMPA).
ProSobee only uses soy protein, which makes it suitable for babies with CMPA.
*Learn more: Hydrolyzed formulas
Carbohydrate Content
Enfamil Gentlease: The main carbohydrate in Enfamil Gentlease is corn syrup solids. Carbohydrates are important as they provide energy to fuel growth and development in infants. Corn syrup solids are a form of glucose that can offer this energy in an easily digestible form.
Enfamil ProSobee: Similar to Enfamil Gentlease, Enfamil ProSobee uses corn syrup solids as its primary carbohydrate source.
No differences in carb content whatsoever. Both use corn syrup solids, which is a common alternative to lactose in US-based formulas. It’s not ideal, however, because of its high sugar content.
*Learn more: Corn Syrup in Baby Formulas
Fats and Oils
Enfamil Gentlease: The fat content in Enfamil Gentlease comes from a blend of vegetable oils including palm olein, soy, coconut, and high oleic sunflower oils. Fats play a critical role in brain development, serving as essential components of cell membranes, particularly in the nervous system. Additionally, the formula contains Mortierella Alpina oil and Schizochytrium sp. oil—to supply important fatty acids like ARA (arachidonic acid) and DHA (docosahexaenoic acid), which are also found in breast milk.
Enfamil ProSobee: Similarly, ProSobee utilizes a combination of vegetable oils like palm olein, coconut, soy, and high oleic sunflower oils to fulfill the fat requirement in a baby’s diet. It mirrors the approach of including Mortierella Alpina oil and Schizochytrium sp. oil to deliver ARA and DHA for proper infant development in terms of vision and cognitive health.
Both formulas use the exact same fat blend, so again, no differences. Palm olein is not an ideal fat source since it has been linked with poor calcium absorption if consumed regularly. This is why some formulas with palm oil or olein contain more calcium content.
*Learn more: Palm Oil in Baby Formula
Prebiotics and Probiotics
Probiotics and prebiotics play a significant role in the health of an infant’s digestive system. Probiotics are beneficial bacteria that can aid in the maintenance of healthy gut flora, while prebiotics are non-digestible fibers that stimulate the growth and activity of these beneficial bacteria. *Read: Prebiotics and Probiotics in Formula
Neither of the two formulas contains prebiotics or probiotics. The reason behind this is that they are supposed to be very easy to digest.
Best Places to Buy Enfamil Gentlease and Enfamil ProSobee
Gentlease
ProSobee
What are the Best Alternatives to Enfamil Gentlease and Enfamil Soy?
Even though these two Enfamil formulas may be suitable for some babies, other alternatives out there are better quality overall. Here are our favorites:
Alternatives to Enfamil Gentlease:
Hipp Comfort: If you’re looking for an organic option similar to Gentlease, Hipp Comfort may suit your needs. This formula is known for its premium quality organic ingredients and contains a remarkable blend of vitamins, minerals, prebiotics (galactooligosaccharides from lactose), and probiotics comparable to natural breast milk constituents. Parents often choose Hipp Comfort not only for its organic certification but also for its reputation in supporting infants with digestive issues.
Hipp HA: Another excellent organic choice is Hipp HA, which stands out for its hydrolyzed protein content—making it easier for babies to digest, much like the proteins in Gentlease. Alongside this feature, it equips your little one with a combination of prebiotic oligosaccharides and probiotics that contribute toward a balanced gut flora. *Read: Hipp HA vs Gentlease
Similac 360 Total Care Sensitive: For those leaning towards Similac products, Similac 360 Total Care Sensitive is considered the best alternative for gentle digestion. It includes 2′-FL HMO—an immune-nourishing prebiotic like those found in human milk—as well as a unique blend of DHA, Lutein, and Vitamin E which support brain development similar to what you’d find in Gentlease. *Read: Similac 360 Total Care Sensitive vs Gentlease
Alternatives to Enfamil ProSobee:
Similac Soy Isomil: As one of the most popular alternatives to ProSobee, Similac Soy Isomil is designed for fussiness and gas relief due to lactose sensitivity. It contains soy protein isolate as its protein source and also offers plant-based phospholipids aimed at supporting cellular development in babies. *Read: Similac Soy vs Enfamil Soy
Gerber Good Start Soy: Gerber Soy provides another soy-based option particularly aimed at babies with lactose intolerance or those on vegetarian diets. It provides essential nutrients such as DHA for brain development while delivering plant-sourced protein enriched with iron.
Last Words
We hope this comparison between Enfamil Gentlease and Enfamil Soy helps you make the best decision for your baby.
If you need extra help, comment below or contact us, and we’ll be happy to help you out.
Happy feeding!
We’re Maria and Alberto, a married couple and educators who are nutrition enthusiasts. Even before we had kids, we were already crazy about nutrition.
We’d read scientific articles, watch videos from nutritionists, and spend hours listening to nutrition podcasts.
Today, we continue doing this, but in a different way, as we’ve learned to sift through the noise and trends. Nutrition, like any other field of knowledge, the more you read and learn, the more you develop a comprehensive understanding of reality, and that’s what has happened to us.
Before having our first child, we focused on learning everything we could about child nutrition, using the same techniques we had already employed, backed by our extensive knowledge in nutrition.
Our mission is to help other parents with their children’s nutrition, to help them become the best versions of themselves.
If we are what we eat and drink, which is absolutely true, let’s do it right!
