Key Differences and Similarities Between Enfamil Enspire and Enfamil Neuropro
| Aspects | Enfamil Enspire | Enfamil NeuroPro |
|---|---|---|
| Brand Reputation | (Close to Breastmilk, Lactoferrin, Non-GMO, Gluten-Free, Suitable for Infants up to 12 Months) | (Trusted by Pediatricians, Non-GMO, Gluten-Free, Suitable for Infants up to 12 Months, HuMO6 Immune Blend) |
| Protein Source & Content | Nonfat milk & Whey protein (2.1g per serve, Contains Lactoferrin) | Nonfat milk & Whey protein (2g per serve) |
| Carbohydrate Source & Content | Lactose (11.2g per serve) | Lactose (11.3g per serve) |
| Fat Source & Content | Palm Olein, Coconut, Soy, High Oleic Sunflower Oils, MFGM, DHA & ARA (5.3g per serve, DHA from Crypthecodinium Cohnii Oil) | Palm Olein, Coconut, Soy, High Oleic Sunflower Oils, MFGM, DHA & ARA (5.3g per serve, DHA from Schizochytrium Sp. Oil) |
| Probiotics & Prebiotics | (2’FL HMO, GOS, PDX Prebiotics) | (2’FL HMO, GOS, PDX Prebiotics) |
| Availability | (Target), (Walmart) | (Target), (Walmart) |
This article compares two popular Enfamil formulas in the US: Enfamil Enspire vs Enfamil Neuropro.
We will analyze their ingredients and nutritional compositions to help you make an informed decision.
Let’s get started!
Related: Enfamil Neuropro vs Similac 360
Our Short Answer
This comparison is like comparing twin formulas. But don’t worry; we always give you an answer.
After analyzing both formulas’ ingredients and nutritional composition, if we had to choose one for our baby, it would be Enfamil Enspire.
This is because the only major difference between the two formulas is that Enfamil Enspire adds lactoferrin, a protein found in milk that has several functions, including regulating iron absorption in the intestine and anti-inflammatory effects.
Removing this ingredient, the few differences between the two formulas are hardly significant.
Before deciding, we recommend you take a look at the alternatives below.
With over 100,000 orders delivered globally since 2019, Organic's Best offers clean, safe, and nutritionally rich formulas and snacks.
Free shipping over $100, commitment to freshness and authenticity.
- Express delivery in 2 to 5 business days
- Sourcing from European manufacturers
- Minimum shelf life of 6 months
- Climate-Controlled Warehouse
Give your little one the best start.
CODE 'BLW' for a 5% discount in all orders
At BLWStore, we may earn a commission from some of the products featured on our website through affiliate partnerships with retailers. We want to be transparent with our readers and let you know that we do not receive any products for special consideration. The commission we earn helps support our website and allows us to continue providing helpful information and product recommendations. Thank you for your support!
Overview of the two formulas
Enfamil Enspire is formulated to mimic breast milk, containing lactoferrin for immune support, DHA for brain development, and dual prebiotics for digestive health.
Enfamil Neuropro is trusted by pediatricians and parents, with DHA and an exclusive HuMO6 immune blend.
It also has a triple prebiotic blend for a healthy gut.
Both are Non-GMO and provide complete nutrition for infants up to 12 months.
Enfamil Enspire
Enfamil Enspire is designed to be as close to natural breast milk as possible. The first and only formula to contain lactoferrin, it aims to support your baby’s immune system. Lactoferrin is a colostrum and breast milk protein, making this formula unique.
Enfamil Enspire also includes DHA (fatty acid) that supports brain development. Moreover, it has a special blend of dual prebiotics shown to promote digestive health.
This formula strives to provide complete nutrition for your child through their first 12 months, making it an excellent choice if you’re searching for non-GMO baby formula.
Enfamil Neuropro
Enfamil Neuropro shares many features with its sibling product, Enspire. It has the endorsement of being the #1 trusted Infant Formula Brand by Pediatricians and Parents in the US.
Neuropro also provides much-needed brain-building nutrients – it sources DHA expertly and offers an exclusive HuMO6 immune blend that gives your infant immune support.
Another unique feature of Neuropro is its triple prebiotic immune blend, which sets it apart from competitors. These prebiotics are great for maintaining a healthy gut in your little one.
Like Enspire, it caters to the all-round nutritional needs of your child for their first 12 months. It’s also designated as non-GMO, ensuring all ingredients are naturally derived.
Nutritional Composition
Enfamil Enspire and Enfamil Neuropro offer similar protein content (around 2g per serving) from nonfat milk and whey protein concentrate.
Enspire stands out with added lactoferrin for immune support.
Both use lactose as the main carbohydrate source (around 11g per serving) and have the same fat content (5.3g per serving) with a blend of vegetable oils, MFGM, DHA, and ARA.
Neuropro uses Schizochytrium Sp. Oil for DHA, while Enspire uses Crypthecodinium Cohnii oil. Learn more
Protein Content
Enfamil Enspire: It provides 2.1g of protein per serving (based on a 5 fl oz serving). The main protein sources are nonfat milk, whey protein-lipid concentrate, and whey protein concentrate. Enspire adds lactoferrin, a protein found in the colostrum (first milk), very beneficial for babies.
Enfamil Neuropro: This infant formula provides slightly less with 2g of protein per serving (5 fl oz). Its protein also comes from nonfat milk, whey protein concentrate, and whey protein-lipid concentrate.
Both formulas are virtually the same regarding protein content and sources.
They use skimmed milk and whey protein concentrate as their primary protein sources, which is what we would expect from a conventional formula.
The only difference that makes Enspire stand out is the addition of lactoferrin, which gives it the upper hand against Neuropro.
Carbohydrate Content
Enfamil Enspire: It delivers 11.2g of total carbohydrate per serving (5 fl oz). Lactose is the primary carbohydrate source that mimics breast milk’s natural sugar.
Enfamil Neuropro: Comes very close with 11.3g total carbohydrate content per serving (5 fl oz). It, too, uses lactose as its main carbohydrate source.
Again, 0 differences in carb content with both formulas using lactose as the only primary carbohydrate source.
This is also the standard practice in standard formulas: no starches, syrups, or maltodextrin included.
Fats and Oils
Enfamil Enspire: It offers 5.3g of total fat per serving (per 5 fl oz serving). The primary sources of fats are vegetable oils, including palm olein, coconut, soy, high oleic sunflower oils, and Mortierella Alpina Oil (ARA) and Docosahexaenoic Acid (DHA).
Enfamil Neuropro: Matches Enspire in delivering 5.3g total fat per serving (5 fl oz). A similarity can also be seen in its choice of fats, including palm olein, coconut, soy, high oleic sunflower oils, and Mortierella Alpina Oil and Docosahexaenoic Acid (DHA).
It’s a draw in fat content, with no differences whatsoever.
Both formulas also add MFGM or Milk Fat Globule Membrane, a fatty acid found in breast milk that is highly beneficial for babies and sources of DHA and ARA.
Enfamil Neuropro uses a slightly better source of DHA (Schizochytrium Sp—oil) than Enspire, which uses Crypthecodinium Cohnii oil.
*Learn more: DHA and ARA in Infant Formula
Probiotics and Prebiotics
Enfamil Enspire and Neuropro contain the same prebiotics: 2′-FL HMO, GOS, and PDX.
Neither formula includes probiotics.
Enfamil Enspire: This formula boasts a 2′-FL HMO, prebiotics found in breast milk, GOS (Galactooligosaccharides), and PDX (polydextrose). All these prebiotics help support the growth of beneficial bacteria in the baby’s gut.
Enfamil Neuropro includes the same prebiotics as Enspire: 2′-FL HMO, GOS, and PDX.
There are no probiotics in either formula.
*Learn more: Prebiotics and Probiotics in Infant Formula
Best Places to Buy Enfamil Neuropro and Enspire
Buy Enfamil Formula at Warlmart
What are the best alternatives to Enfamil Neuropro and Enspire?
Kendamil Organic: This is our top alternative, thanks to whole milk and real HMOs. It avoids using processed skimmed milk products and offers better nutrient value making it an excellent option for those who appreciate close-to-natural solutions. *Read: Kendamil vs Enfamil
Bobbie: A standout choice from the US, Bobbie is recognized for being organic with a pure and simple ingredients list that eliminates any unnecessary additives giving you peace of mind about what’s going into your babe’s body. *Read: Bobbie vs Enfamil
Holle: Holle is tough to beat if you want purity and natural organic ingredients. With its Demeter certification ensuring biodynamic farming, it offers one of the cleanest, healthiest formulas on the market. *Read: Holle vs Enfamil
Last Words
We hope this comparison between Enfamil Enspire and Neuropro helps you make an informed decision for your baby.
We strongly encourage you to read about our recommended alternatives above before making any purchasing decisions.
If you have further questions, leave a comment, and we’ll get back to you in less than one day.
Happy feeding!
We’re Maria and Alberto, a married couple and educators who are nutrition enthusiasts. Even before we had kids, we were already crazy about nutrition.
We’d read scientific articles, watch videos from nutritionists, and spend hours listening to nutrition podcasts.
Today, we continue doing this, but in a different way, as we’ve learned to sift through the noise and trends. Nutrition, like any other field of knowledge, the more you read and learn, the more you develop a comprehensive understanding of reality, and that’s what has happened to us.
Before having our first child, we focused on learning everything we could about child nutrition, using the same techniques we had already employed, backed by our extensive knowledge in nutrition.
Our mission is to help other parents with their children’s nutrition, to help them become the best versions of themselves.
If we are what we eat and drink, which is absolutely true, let’s do it right!
